Improved contact prediction in proteins: Using pseudolikelihoods to infer Potts models
نویسندگان
چکیده
منابع مشابه
Improved contact prediction in proteins: using pseudolikelihoods to infer Potts models.
Spatially proximate amino acids in a protein tend to coevolve. A protein's three-dimensional (3D) structure hence leaves an echo of correlations in the evolutionary record. Reverse engineering 3D structures from such correlations is an open problem in structural biology, pursued with increasing vigor as more and more protein sequences continue to fill the data banks. Within this task lies a sta...
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ژورنال
عنوان ژورنال: Physical Review E
سال: 2013
ISSN: 1539-3755,1550-2376
DOI: 10.1103/physreve.87.012707